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Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome. Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): Anxiety or nervousness. Basic Information. Mean effective half-life: 2 to 3 hours. Time to steady-state: 40 to 90 minutes. Terminal phase half-life: 2 to 3 hours. Buspirone has an oral bioavailability of roughly 5 percent or lower due to first pass metabolism. This means that a very low percentage of the medication gets to the systemic circulation in an unchanged state.Tropicanna Dispensary and Weed Delivery is Anaheim, CA's favorite Cannabis Dispensary. Visit our site for info about our Anaheim, CACannabis Dispensary!Usual Adult Dose for Anxiety. Initial Dose: 7.5 mg orally 2 times a day. Maintenance Dose: Dosage may be increased 5 mg per day at intervals of 2 to 3 days, as needed. Maximum Dose: 60 mg per day. Use: Management of anxiety disorders or the short-term relief of anxiety symptoms.

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